Tag Archive for London

Cancer is not a disease of the rich but a global health priority, say experts

London, Aug 16 (ANI): Medical experts have called for action on cancer, saying that it is not a ”disease of the rich” but a global health priority.

"The integration of cancer prevention and care where both are needed is precisely what we need to do if we are to make the response to the challenge as global as cancer itself,” Lancet quoted Paul Farmer, chair of the HMS department of global health and social medicine, as saying.

“There are clearly effective interventions that can prevent or ease suffering due to many malignancies, and that is surely our duty as physicians or policy makers or health advocates,” he added.

Comparing cancer fatality rates between low- and high-income countries reveals stark disparities.

Fatality rates in low-income countries are 75 percent, in lower middle-income 72 percent, and in upper middle-income 64 percent.

This enormous difference in survival – particularly for many highly treatable and curable cancers such as cervical, breast, testicular and acute lymphoblastic leukemia in children – denote the scope of action.

"As a person living with cancer, diagnosed in a developing country, I believe we must address this glaring inequity. Evidence shows that this can be done," said Felicia Knaul.

“To correct this situation we must address the staggering ”5/80 cancer disequilibrium,” that is, the fact that low- and middle-income countries account for almost 80 percent of the burden of disease due to cancer yet receive only 5 percent of global resources devoted to deal with this emerging challenge," said Julio Frenk.

Raise global awareness of the impact of cancer on developing countries, defining the packages of essential services and treatments, increasing access to the best treatment for cancer and evaluating successful service delivery models in different economic and health system settings are just some of the goals the medical community plans to work towards.

According to Larry Shulman, "Access to life-saving cancer care is a human right, and must be brought to those in developing countries.

“We have shown we can do this in the treatment of other illnesses, and we can and must do this with cancer care. This should be viewed as an imperative rather than as an option."

The paper is published online in the Lancet. (ANI)

Rare protein may regulate cocaine intake

London, Aug 16 (ANI): A new study has found that a regulatory protein best known for its role in a rare genetic brain disorder may help in controlling the intake of cocaine.
According to a recent study in rats, researchers at the Scripps Research Institute found that cocaine consumption increased levels of a regulatory protein called MeCP2 that shuttles back to the nucleus to influence gene expression in the brains of rats.
As levels of MeCP2 increased in the brain, so did the animals” motivation to self-administer cocaine.
This suggests that MeCP2 plays a crucial role in regulating cocaine intake in rats and perhaps in determining vulnerability to addiction.
"This discovery, using an animal model of addiction, has exposed an important effect of cocaine at the molecular level that could prove key to understanding compulsive drug taking," Nature quoted Nora D. Volkow of NIDA as saying.
"It should open up new avenues of research on the causes and ways to counter the behavioral changes linked to addiction in humans," Volkow said.
Researchers discovered that the brain”s balance between MeCP2 and miRNA-212 ultimately regulates cocaine intake. When the balance shifts toward MeCP2, cocaine intake increases.
When the balance shifts toward miRNA-212, cocaine intake decreases. What determines the balance is not yet understood, however, and will be the focus of future research.
"This study represents another piece in the puzzle of determining vulnerability to cocaine addiction," said Paul J. Kenny of Scripps.
"If we can continue putting the pieces together, we may be able to determine whether there are viable treatments for this condition," Kenny added.
The study was published in the journal Nature Neuroscience.

Chinese porn star felt like king of the world after satisfying 100 women

London, Aug 16 (ANI): The leading man of a Chinese 3D porn flick has revealed that when he had to do a scene where he had to satisfy 100 women, it made him feel like the king of the world.

Hiro Hayana, 35, who will be starring in, what is hoped to be the world’s first-ever 3D porn flick, had found his first erotic film to be daunting, but he quickly got the hang of it.

“I felt like the king of the world,” the Sun quoted him as saying.

The 2million pounds erotic epic ‘Sex and Zen: Extreme Ecstasy’ will be directed by Christopher Sun, who is hoping it will be a box office hit when it is released next year.

Director Sun is in a race against time to complete the project because Italian director Tinto Brass has already announced he will produce a 3D remake of his 1979 erotic film ‘Caligula’.

“I don’t think they can beat us. This is the future of the movie business — it’s human nature to want to see things in 3D,” producer Stephen Shiu added.

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